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- Title
Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases.
- Authors
Campos, João Henrique; Soares, Rodrigo Pedro; Ribeiro, Kleber; Cronemberger Andrade, André; Batista, Wagner Luiz; Torrecilhas, Ana Claudia; Andrade, André Cronemberger
- Abstract
Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases.
- Subjects
EXTRACELLULAR matrix proteins; INFLAMMATION; COMMUNICABLE diseases; VACCINATION; THERAPEUTICS; TUMOR treatment; INFLAMMATION prevention; ANIMALS; CELL communication; CELLULAR signal transduction; PREVENTION of communicable diseases; IMMUNIZATION; TUMORS
- Publication
Journal of Immunology Research, 2015, Vol 2015, p1
- ISSN
2314-8861
- Publication type
journal article
- DOI
10.1155/2015/832057