We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Seroprevalence of Parvovirus B19 among Kidney Transplant Recipients: A Single-Center Study.
- Authors
Khameneh, Z. Rostamzadeh; Sepehrvand, N.
- Abstract
Background: Parvovirus B19 is a DNA virus, which is responsible for several various diseases in human. Parvovirus B19-induced persistent anemia is one of its manifestations, which is relatively common in transplant recipients. Objective: To investigate the seroprevalence of parvovirus B19 among kidney transplant recipients. Methods: 91 transplant recipients were selected at random and investigated for several variables including age, sex, educational status and history of hemodialysis (HD), blood transfusion, and immunosuppressive therapy. Blood samples were collected via venipuncture and evaluated for anti-parvovirus B19 IgG antibody using enzyme linked immunosorbent assay (ELISA). Results: All recipients had anemia; 72.5% of them had severe anemia (Hb≤11 in men and ≤10 g/dL in women). 63 patients (69%) were seropositive for parvovirus B19. There was no significant difference in age, sex, educational status, and history of blood transfusion, HD, and the immunosuppressive therapy between seropositive and seronegative groups. Conclusion: The seroprevalence of parvovirus B19 was relatively high among kidney transplant recipients. Anemia is a common problem in these patients and often remains under-treated. However, our study failed to find a correlation between the severity of anemia and seropositivity of parvovirus B19.
- Subjects
PARVOVIRUSES; DNA viruses; TRANSPLANTATION of organs, tissues, etc.
- Publication
International Journal of Organ Transplantation Medicine, 2016, Vol 7, Issue 2, p129
- ISSN
2008-6490
- Publication type
Abstract