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- Title
An open chat with...Beáta Vertessy.
- Authors
Tsagakis, Ioannis; Vertessy, Beáta; Wright, Duncan
- Abstract
Uracil and thymine nucleobases only differ by a single methyl group, and it is fascinating to understand the different occurrences of these two bases in RNA versus DNA. When I started working in the uracil-DNA field, it was already known that DNA could contain uracil either via thymine replacing misincorporation or via deamination of cytosine. We first showed the significance of uracil-DNA in the development of I Drosophila i (fruitfly) and then aimed to characterize the quantitative patterns of uracil genomic distribution in different models, a task which required us to develop new tools.
- Subjects
BASE pairs; NUCLEOTIDE sequence; HUMAN DNA; BIOPHYSICS; VOCATIONAL guidance
- Publication
FEBS Open Bio, 2021, Vol 11, Issue 2, p338
- ISSN
2211-5463
- Publication type
Article
- DOI
10.1002/2211-5463.13077