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- Title
Impacto da atenção farmacêutica na função pulmonar de pacientes com asma grave.
- Authors
Zanghelini, Fernando; de Arimatea Rocha Filho, José; Menezes Carvalho, André Luis; da Silva, André Santos
- Abstract
The aim of the present study was to analyze the influence of pharmaceutical care on the optimization of therapeutic results in patients with severe asthma using formoterol combined with budesonide. Evaluations were performed with spirometry, the Dáder Pharmacotherapeutic Follow Up method and Asthma Control Test (ACT™). Twenty-six patients (mean age: 55 ± 11 years; 22 females) were monitored for not less than six months. Twenty-two patients (84.6%) had more than one health condition associated with severe asthma and 24 (92%) made use of two or more drugs. The research identified 58 negative results associated with medication (NRM), corresponding to an individual incidence of 2.2 ± 0.99 NRMs per patient. The most frequent NRM was a non-quantitative uncertainty identified in 11 patients (43%), with 31% of cases due to adverse reactions to the drug. Sixty-five pharmaceutical interventions were carried out to resolve the NRMs, with a mean of 2.5 ± 1.2 per patient, 85% of which occurred in the pharmacy without the need to see a doctor. Subsequently to medical treatment following pharmaceutical intervention, all patients experienced a clear improvement in symptoms (p < 0.05). However, two subjects (7.6%) continued to experience uncontrolled asthma. The present findings reveal a need for the pharmacotherapeutic monitoring of patients with severe uncontrolled asthma in order to optimize clinical outcomes.
- Subjects
BUDESONIDE; FORMOTEROL; ASTHMA; PHARMACY; SYMPTOMS
- Publication
Revista de Ciências Farmacêuticas Básica e Aplicada, 2013, Vol 34, Issue 3, p379
- ISSN
1808-4532
- Publication type
Article