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- Title
Pediatric Liver Transplantation: Our Experiences.
- Authors
Basturk, Ahmet; Artan, Reha; Yılmaz, Aygen; Sayar, Ersin; Dinçhan, Ayhan; Aliosmanoğlu, İbrahim; Erbiş, Halil; Aydınlı, Bülent
- Abstract
Objective: The aim of our study was to evaluate our liver transplant pediatric patients and to report our experience in the complications and the long-term follow-up results. Materials and Methods: Patients between the ages of 0 and 1 8 years, who had liver transplantation in the organ transplantation center of our university hospital between 1997 and 201 6, were included in the study. The age, sex, indications for the liver transplantation, complications after the transplantation, and long-term follow-up findings were retrospectively evaluated. The obtained results were analyzed with statistical methods. Results: In our organ transplantation center, 62 pediatric liver transplantations were carried out since 1997. The mean age of our patients was 7.3 years (6.5 months-17 years). The 4 most common reasons for liver transplantation were: Wilson's disease (n=1 0; 1 6.3%), biliary atresia (n=9; 1 4.5%), progressive familial intrahepatic cholestasis (n=8; 1 2.9%), and cryptogenic cirrhosis (n=7; 1 1.3%). The mortality rate after transplantation was 19.6% (1 2 of the total 62 patients). The observed acute and chronic rejection rates were 34% and 4.9%, respectively. Thrombosis (9.6%) was observed in the hepatic artery (4.8%) and portal vein (4.8%). Bile leakage and biliary stricture rates were 3 1% and 1 1%, respectively. 1-year and 5-year survival rates of our patients were 87% and 84%, respectively. Conclusion: The morbidity and mortality rates in our organ transplantation center, regarding pediatric liver transplantations, are consistent with the literature.
- Subjects
CIRRHOSIS of the liver; HEPATOLENTICULAR degeneration diagnosis; BILIARY atresia; CHOLESTASIS; AGE distribution; LIVER; LIVER failure; LIVER transplantation; PEDIATRICS; SEX distribution; SURGICAL complications; SURVIVAL; THROMBOSIS; RETROSPECTIVE studies; DESCRIPTIVE statistics; DIAGNOSIS
- Publication
Eurasian Journal of Medicine, 2016, Vol 48, Issue 3, p209
- ISSN
1308-8734
- Publication type
Article
- DOI
10.5152/eurasianjmed.2016.0147