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- Title
New evidence in diagnosis of pulmonary embolism during pregnancy.
- Authors
Viau-Lapointe, Julien; Arsenault, Marie-Pier
- Abstract
Diagnosis of pulmonary embolism (PE) in pregnancy is notoriously difficult and lacking high quality evidence. Three studies (DiPEP, ARTEMIS and CT-PE-Pregnancy) evaluating a systematic approach to PE diagnosis have recently been published. DiPEP is a retrospective case-control study that found a poor utility of clinical decision rules or D-dimer testing for PE diagnosis in pregnancy. ARTEMIS and CT-PE-Pregnancy are well conducted prospective management studies that proposed two algorithms with different clinical decision rules and D-dimer criteria for the diagnosis of PE in pregnancy. They included few events in high risk patients, which makes difficult the assessment of both algorithm's safety in women with a high probability of PE. Considering this new evidence, D-dimer testing might be useful to avoid radiation imaging in pregnant women considered at low risk for PE. In contrast, a negative D-dimer cannot be considered sufficiently safe to rule out PE when clinicians estimate that PE is the most likely diagnosis.
- Subjects
ALGORITHMS; PULMONARY embolism; FIBRIN fibrinogen degradation products; PREGNANCY
- Publication
Obstetric Medicine (1753-495X), 2020, Vol 13, Issue 3, p120
- ISSN
1753-495X
- Publication type
Article
- DOI
10.1177/1753495X19875589