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- Title
Unusual case of splenic sarcoidosis without morphological lesions detected by PET-CT in a patient with breast cancer: functional imaging between pitfalls and therapeutic guide.
- Authors
Paone, Gaetano; Di Lascio, Simona; Azzola, Andrea; Mazzucchelli, Luca; Pagani, Olivia
- Abstract
A 60-year-old woman under treatment with letrozole for metastatic breast cancer underwent 18F-FDG PET-CT for restaging. A new widespread intense splenic FDG uptake without nodular lesions and multiple FDG-avid mediastinal and abdominal nodes were observed. Based on these findings, a nodal and transbronchial lung biopsy was performed. Histological results were compatible with sarcoidosis. The patient began steroid treatment and 6 weeks after a PET-CT showed normalisation of both splenic and nodal uptake. In our case, 18F-FDG PET-CT has been useful in detecting a rare case of splenic sarcoidosis without typical nodular lesions on CT images, impacting the patient's treatment and prognosis.
- Subjects
SARCOIDOSIS; POSITRON emission tomography; BREAST cancer treatment
- Publication
Ecancermedicalscience, 2017, Vol 11, Issue 752-769, p1
- ISSN
1754-6605
- Publication type
Article
- DOI
10.3332/ecancer.2017.766