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- Title
Current Challenges Facing the Translation of Brain Computer Interfaces from Preclinical Trials to Use in Human Patients.
- Authors
Murphy, Maxwell D.; Guggenmos, David J.; Bundy, David T.; Nudo, Randolph J.; Brown, Euan Robert
- Abstract
Current research in brain computer interface (BCI) technology is advancing beyond preclinical studies, with trials beginning in human patients. To date, these trials have been carried out with several different types of recording interfaces. The success of these devices has varied widely, but different factors such as the level of invasiveness, timescale of recorded information, and ability to maintain stable functionality of the device over a long period of time all must be considered in addition to accuracy in decoding intent when assessing the most practical type of device moving forward. Here, we discuss various approaches to BCIs, distinguishing between devices focusing on control of operations extrinsic to the subject (e.g., prosthetic limbs, computer cursors) and those focusing on control of operations intrinsic to the brain (e.g., using stimulation or external feedback), including closed-loop or adaptive devices. In this discussion, we consider the current challenges facing the translation of various types of BCI technology to eventual human application.
- Subjects
BRAIN-computer interfaces; CLOSED loop systems; PHONOLOGICAL decoding; TRANSLATIONS; CLINICAL trials
- Publication
Frontiers in Cellular Neuroscience, 2016, p1
- ISSN
1662-5102
- Publication type
Article
- DOI
10.3389/fncel.2015.00497