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- Title
Bacillary angiomatosis triggered by severe trauma in a healthy Caucasian patient: A case report.
- Authors
Balaban, Mihaela; Ioana Nedelcu, Roxana; Balmes, Gabriela; Adela Todorovic, Teodora; Brinzea, Alice; Nichita, Luciana; Gabriela Popp, Cristiana; Theodor Andrei, Razvan; Andrada Zurac, Sabina; Adriana Ion, Daniela; Turcu, Gabriela
- Abstract
Bacillary angiomatosis represents a cutaneous and systemic infection caused by Bartonella species, typically described in the past in HIV-positive patients or associated with immunodeficiencies. More recent case reports had brought into attention the probability that this entity may manifest in otherwise healthy individuals, triggered by trauma and skin burns. The physiopathology of this neoproliferative process is based on the production of angiogenetic molecules, such as vascular endothelial growth factor (VEGF) and IL-8. In case of an inadequate treatment, the evolution can be fatal, with a systemic dissemination of the abscesses within the gastro-intestinal tract, respiratory tract, brain and bones. The appropriate therapy is with oral erythromycin and doxycycline, but several treatments such as cephalosporins, penicillins, macrolides, aminoglycosides, rifampin, dapsone, ciprofloxacin, have been tried with favorable results. Herein we present the case of a Caucasian patient, seronegative for HIV, who developed multiple vascular papules and nodules on the face, after a severe trauma and which healed after an adequate antibiotic therapy with oral clarithromycin.
- Subjects
VASCULAR endothelial growth factors; ERYTHROMYCIN; BRAIN abscess
- Publication
Experimental & Therapeutic Medicine, 2020, Vol 20, Issue 1, p56
- ISSN
1792-0981
- Publication type
Article
- DOI
10.3892/etm.2019.8260