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- Title
DSA-guided percutaneous sclerotherapy for children with oropharyngeal low-flow venous malformation.
- Authors
Song, Dan; Guo, Lei; Sheng, Hui; Li, Jing; Wang, Liang; Wu, Changhua; Wang, Changfeng; Niu, Yanli; Zeng, Qingshi
- Abstract
The present study investigated the efficacy and safety of digital subtraction angiography-guided 3% polidocanol foam sclerosing agent, as well as the combination of pingyangmycin and dexamethasone, for the treatment of children with oropharyngeal low-flow venous malformation. A total of 27 children with 35 lesions with oropharyngeal low-flow venous malformation were included. The subjects were randomly divided into Groups A (13 patients with 16 lesions, treated with 3% polidocanol foam sclerosing agent) and B (14 patients with 19 lesions, treated with pingyangmycin + dexamethasone), respectively. The clinical efficacies and adverse reactions were analyzed and compared between these two groups. The average number of treatment times for Group A was 2.45±0.6, with an efficacy rate of 87.50%, while the average number of treatment times for Group B was 2.07±0.4, with an efficacy rate of 84.21%. No significant difference was found in the average treatment times or efficacy rates between Groups A and B. In addition, the adverse reaction incidence for Groups A and B were 38.46 and 14.29%, respectively, with statistically significant differences between these two groups. The combination of pingyangmycin and dexamethasone was safe and effective in treating children with oropharyngeal low-flow venous malformation, with fewer adverse reactions and is worthy of clinical promotion.
- Subjects
SCLEROTHERAPY; HUMAN abnormalities; SURFACE active agents
- Publication
Experimental & Therapeutic Medicine, 2020, Vol 19, Issue 5, p3405
- ISSN
1792-0981
- Publication type
Article
- DOI
10.3892/etm.2020.8581