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- Title
Clinical responses in allografted acute leukaemia patients with resistant disease using a combined chemo-immunotherapeutic treatment strategy.
- Authors
Torelli, Giovanni F.; Natalino, Fiammetta; Barberi, Walter; Maggio, Roberta; Peragine, Nadia; De Propris, Maria S.; Piciocchi, Alfonso; Valle, Veronica; Iannella, Emilia; Iori, Anna P.; Guarini, Anna; Foà, Robin
- Abstract
The article presents a study that evaluates the immunological and clinical effects of a chemo-immunotherapeutic treatment strategy including chemotherapy in patients with allografted acute leukemia. The study uses non-parametric Wilcoxon test to evaluate the differences in percentage of each parameter between the two groups of patients. The results affirmed the observations in animals and humans which suggest the possibility of donor lymphocytes activation when infused after chemotherapy.
- Subjects
LEUKEMIA treatment; DRUG therapy; LYMPHOCYTES; HOMOGRAFTS; ACUTE leukemia; PATIENTS
- Publication
British Journal of Haematology, 2010, Vol 151, Issue 1, p86
- ISSN
0007-1048
- Publication type
Letter
- DOI
10.1111/j.1365-2141.2010.08291.x