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- Title
Catalyst‐Free Three‐Component Synthesis of α‐Amino Phosphonates.
- Authors
Soliya, Sudha; Kuperkar, Ketan; Ashalu, Kashamalla Chinna; Naveen, Togati
- Abstract
An efficient and environmentally friendly method for the synthesis of α‐amino phosphonates has been reported using the one‐pot, three‐component reaction of various substituted anilines and benzaldehydes with diethyl phosphite in acetonitrile at 100 °C. The advantages of this method are catalyst‐free and works well with a broad substrate scope of various aromatic anilines and aldehydes containing both electron‐donating and withdrawing groups.
- Subjects
PHOSPHONATES; BENZALDEHYDE; AROMATIC aldehydes; ACETONITRILE; SUSTAINABLE chemistry
- Publication
Asian Journal of Organic Chemistry, 2024, Vol 13, Issue 3, p1
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.202300572