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- Title
Pyomelanin is produced by Shewanella algae BrY and affected by exogenous iron.
- Authors
Turick, Charles E.; Caccavo Jr., Frank; Tisa, Louis S.
- Abstract
Melanin production by Shewanella algae BrY occurred during late- and (or) post-exponential growth in lactate basal salts liquid medium supplemented with tyrosine or phenylalanine. The antioxidant ascorbate inhibited melanin production but not production of the melanin precursor homogentisic acid. In the absence of ascorbate, melanin production was inhibited by the 4-hydroxyphenylpyruvate dioxygenase inhibitor sulcotrione and by concentrations of Fe >= 0.38 mmol·L-1. These data support the hypothesis that pigment production by S. algae BrY was a result of the conversion of tyrosine or phenylalanine to homogentisic acid, which was excreted, auto-oxidized, and self-polymerized to form pyomelanin. Pyomelanin production by S. algae BrY may play an important role in the biogeochemical cycling of Fe in the environment.
- Subjects
SHEWANELLA alga; SHEWANELLA; SHEWANELLA putrefaciens; MELANINS; MELANOCYTES; AMINO acids; PHENYLALANINE; TYROSINE; AMINO compounds
- Publication
Canadian Journal of Microbiology, 2008, Vol 54, Issue 4, p334
- ISSN
0008-4166
- Publication type
Article
- DOI
10.1139/W08-014