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- Title
Hydrogen Sulfide Regulates Homeostasis of Mesenchymal Stem Cells and Regulatory T Cells.
- Authors
Yang, R.; Liu, Y.; Shi, S.
- Abstract
Hydrogen sulfide (H2S) has long been known as a toxic gas. However, recently accumulated evidence suggests that H2S contributes to a variety of physiologic and pathologic processes. Endogenous H2S production is regulated by multiple enzymes that are differentially expressed in the cardiovascular, neuronal, immune, renal, respiratory, gastrointestinal, reproductive, liver, and endocrine systems. Alteration of H2S metabolism may affect multiple signaling pathways and tissue homeostasis. The growing number of diverse targets for which H2S serves as a gasotransmitter has been extensively reviewed elsewhere. In this review, the authors discuss current emerging evidence that H2S regulates mesenchymal stem cell and T-cell functions.
- Subjects
ENDOGENOUS hydrogen sulfide; HOMEOSTASIS; MESENCHYMAL stem cells; T cells; REGENERATION (Biology)
- Publication
Journal of Dental Research, 2016, Vol 95, Issue 13, p1445
- ISSN
0022-0345
- Publication type
journal article
- DOI
10.1177/0022034516659041