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- Title
Epstein-Barr Virus--Associated Smooth Muscle Tumor of the Iris in a Patient With Transplant.
- Authors
Le Yu; Aldave, Anthony J.; Glasgow, Ben J.
- Abstract
Epstein-Barr virus infection has been linked to the development of smooth muscle tumors in immunocompromised patients with organ transplants and acquired immunodeficiency syndrome. A 52-year-old female recipient of a renal transplant presented with enlarging masses of the left iris. Incisional biopsy of the mass revealed a smooth muscle tumor of the iris. Epstein-Barr virus infection was confirmed by in situ hybridization for Epstein-Barr virus-encoded, small RNA in tumor cells. Eight months after total iridectomy the patient was free of disease. Although the prognosis and classification of Epstein-Barr virus- associated smooth muscle tumors are controversial, mortalities caused by these tumors are rare.
- Subjects
EPSTEIN-Barr virus diseases; SMOOTH muscle tumors; IRIS (Eye); DIAGNOSTIC use of in-situ hybridization; KIDNEY transplant patients; BIOPSY; CANCER cell proliferation; TUMORS
- Publication
Archives of Pathology & Laboratory Medicine, 2009, Vol 133, Issue 8, p1238
- ISSN
0003-9985
- Publication type
Article
- DOI
10.5858/133.8.1238