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- Title
Development of persistent HCV genotype 3a infection cell culture model in huh-7 cell.
- Abstract
The article discusses a study which was aimed to develop a persistent Hepatitis C virus (HCV) genotype 3a infectious cell culture model. The study also evaluated persistent HCV genotype 3a replication in the infection model by silencing HCV genotype 3a replication with siRNA targeting highly conserved core region. The study concluded that the infection cell culture model consistently replicate HCV genotype 3a for more than 1 month.
- Subjects
VIRAL replication; HEPATITIS C virus; CELL culture; PERSISTENT viral diseases; POLYMERASE chain reaction; WESTERN immunoblotting
- Publication
Virology Journal, 2012, Vol 9, Issue 1, p11
- ISSN
1743-422X
- Publication type
Article
- DOI
10.1186/1743-422X-9-11