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- Title
Intraductal papillary mucininous neoplasm of the bile ducts: multimodality assessment with pathologic correlation.
- Authors
Takanami, Kentaro; Yamada, Takayuki; Tsuda, Masashi; Takase, Kei; Ishida, Kazuyuki; Nakamura, Yasuhiro; Kanno, Atsushi; Shimosegawa, Tooru; Unno, Michiaki; Takahashi, Shoki
- Abstract
Mucin-producing intraductal papillary neoplasm (adenocarcinoma/adenoma) in the bile duct is becoming recognized as a specific type of neoplasm. Since, it bears a striking similarity to intraductal papillary mucinous neoplasms of the pancreas with regard to its histopathologic features, the term 'intraductal papillary mucinous neoplasms of the bile duct' (IPMN-B) is frequently used, although no definite terminology or definition has been decided by World Health Organization. This neoplasm lacks ovarian-like stroma and communicates with the bile ducts, unlike biliary mucinous cystic neoplasm (MCN). On the other hand, malignant IPMN-B is categorized as an intraductal-growth type of intrahepatic cholangiocarcinoma (ICC). In comparison to other types of ICC, such as the mass-forming type and periductal-infiltrating type that have poor resectability and an unfavorable prognosis, malignant IPMN-B can be resected and demonstrates a more favorable prognosis. Meanwhile, unlike biliary MCN that is usually confined in a closed cyst, IPMN-B can spread along the mucosal surface of the bile ducts, and it should be widely resected. Therefore, multimodality assessment is needed to ensure the correct diagnosis of IPMN-B. We herein review the imaging findings of IPMN-B with pathologic correlation.
- Subjects
DUCTAL carcinoma; PAPILLARY carcinoma; BILE duct tumors; STATISTICAL correlation; ADENOCARCINOMA; HISTOPATHOLOGY; PROGNOSIS
- Publication
Abdominal Imaging, 2011, Vol 36, Issue 4, p447
- ISSN
0942-8925
- Publication type
Article
- DOI
10.1007/s00261-010-9649-x