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- Title
颅内孤立性纤维性肿瘤/血管周细胞瘤的临床特点及复发影响因素分析.
- Authors
徐宏浩; 黄庆玖; 陈永严; 刘翔; 杨坤; 胡新华; 张锐
- Abstract
Objective To investigate the clinical manifestations, therapies and prognostic factors of intracranial solitary fibrous tumor/ hemangiopericytoma ( SFT/ HPC) . Methods The clinical data of 19 patients with intracranial SFT/ HPC were retrospectively analyzed. Results In the study, there were 10 male and 9 female patients ranged from 18 to 71 years old ( mean 49. 5 ± 13. 9 years and median 59 years) were recruited. The duration of the patients' disease ranged from days to 2 years. All patients underwent microsurgical treatment. Postoperative CT or MRI examination of the head showed total tumor resection in 16 patients and subtotal tumor resection in 3 patients. 13 patients were follow-up for 6 - 132 months, with an average of 46. 0 ± 37. 9 months. The recurrence time of 6 patients was 60 - 79 months after surgery, 72. 0 ± 7. 1 months on average. No patients had extracranial or intracranial distant metastasis. At the final follow-up, the recurrence rate of patients with total tumor resection was 36. 4% and that of patients with subtotal tumor resection was 100%, and the difference between the two groups was statistically significant ( P < 0 . 05) . The recurrence rate of postoperative adjuvant radiotherapy patients was 20%, and that of non-radiotherapy patients was 33. 3 %, the difference between the two groups was not statistically significant( P > 0. 05 ) . Conclusions Intracranial SFT/ HPC is a rare entity with short course duration. Surgery is the primary option. Short-term control is favorable while long-term recurrent rate is still high. Total tumor resection can significantly reduce postoperative recurrence rate. The effects of postoperative radiotherapy on recurrence rate needs further study.
- Publication
Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi, 2020, Vol 17, Issue 6, p680
- ISSN
1672-7770
- Publication type
Article
- DOI
10.3969/j.issn.1672-7770.2020.06.016