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- Title
EARLY CARDIOVASCULAR MRI POST SUCCESSFUL REPERFUSION OF ACUTE MYOCARDIAL INFARCTION: AN EXPLORATORY STUDY.
- Authors
NOR HANIM, MOHD AMIN; ASRI, SAID; KENG TAT KOH; YEN YEE OON; FONG ALAN YEAN YIP; YEE LING CHAM; SIAN KONG TAN; NING ZAN KHIEW; KUAN LEONG YEW; CHI YEN VOON; TIONG KIAM ONG
- Abstract
Post-myocardial infarction (MI) patients has varied outcome despite successful reperfusion. Our study aimed to use cardiac magnetic resonance imaging (CMR) to explore parameters that may influence outcome in successfully reperfused post-MI patients. We used left ventricular (LV) remodelling and major adverse cardiovascular event (MACE) at 6 months as a pooroutcome indicator. Consecutive patients admitted to Sarawak Heart Centre from Dec 2012 to Nov 2014 with acute anterior or inferior ST elevation MI were screened. A total of 101 patients with TIMI-3 flow were recruited. Patients underwent CMR imaging during the index admission, and another between 3 to 6 months later. LV remodelling occurred in 21.8% while microvascular obstruction (MVO) in 38.6% of patients. LV infarct size and MVO were significant in those who developed LV remodelling, while door-to-perfusion time and total-ischaemic time were not significantly different. MACE was significant in patients with larger infarcts but not significant in patients with MVO. LV infarct size was also significant in those who had reverse LV remodelling. These results suggest that early CMR measurement of infarct size and detection of MVO has the potential to predict LV improvement or deterioration at 6 months.
- Subjects
MYOCARDIAL infarction; REVASCULARIZATION (Surgery)
- Publication
Malaysian Applied Biology, 2018, Vol 47, Issue 1, p181
- ISSN
0126-8643
- Publication type
Article