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- Title
Parallel Chromatography -- Double Your Money.
- Authors
Nelson, Michael D.; Dolan, John W.
- Abstract
The article focuses on the parallel chromatography (LC) separations by using column-switching techniques. It is used routinely to desalt samples or remove strongly retained materials from injected samples before they reach the analytical column. A column-switching set-up was used, that can run the same sample through an array of six different columns in an overnight run to help speed column selection during method development. A typical example of the need for rapid turnaround is a rising dose-tolerance study, which subjects are dosed with a drug.
- Subjects
MULTIDIMENSIONAL chromatography; CHROMATOGRAPHIC analysis; ANALYTICAL chemistry; PHASE partition; MASS spectrometry; DRUGS
- Publication
LC-GC Europe, 2004, Vol 17, Issue 5, p272
- ISSN
1471-6577
- Publication type
Article