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- Title
Clinical features of gastric cancer discovered after successful eradication of.
- Authors
Kamada, T.; Hata, J.; Sugiu, K.; Kusunoki, H.; Ito, M.; Tanaka, S.; Inoue, K.; Kawamura, Y.; Chayama, K.; Haruma, K.
- Abstract
: Eradication ofHelicobacter pyloriis expected to prevent the development of gastric cancer. However, gastric cancer is sometimes discovered after successful eradication ofH. pylori.: To conduct a prospective study to determine the clinical features of patients who underwent successful eradication and were later diagnosed with gastric cancer.: A total of 1787 patients (1299 males and 488 females; mean age, 58.2 years; range: 15–84) who underwent successful eradication therapy between April 1994 and March 2001 were our study subjects.: Gastric cancer occurred at a rate of 1.1% (20 of 1787) during the follow-up period. Gastric cancer comprises six of 105 (5.7%) with early gastric cancer after endoscopic resection, 12 of 575 (2.1%) with gastric ulcer and two of 453 (0.4%) with atrophic gastritis. Gastric cancer did not develop in any patient with duodenal ulcer. All patients with gastric cancer had baseline severe atrophic gastritis in the corpus.: Careful endoscopic examination is necessary even after successful eradication ofH. pyloriin patients with early gastric cancer or gastric ulcer with severe mucosal atrophy in the corpus.
- Subjects
GASTROINTESTINAL diseases; CANCER patients; HELICOBACTER pylori; CANCER prevention; THERAPEUTICS; ENDOSCOPY; SURGICAL excision; GASTRITIS; MUSCULAR atrophy
- Publication
Alimentary Pharmacology & Therapeutics, 2005, Vol 21, Issue 9, p1121
- ISSN
0269-2813
- Publication type
Article
- DOI
10.1111/j.1365-2036.2005.02459.x