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- Title
The Role of Race and Economic Characteristics in the Presentation and Survival of Patients With Surgically Resected Non-Small Cell Lung cancer.
- Authors
Varlotto, John M.; McKie, Kerri; Voland, Rickie P.; Flickinger, John C.; DeCamp, Malcolm M.; Maddox, Debra; Rava, Paul Stephen; Fitzgerald, Thomas J.; Walsh, William; Oliveira, Paulo; Rassaei, Negar; Baima, Jennifer; Karl Uy
- Abstract
Background: Little is understood regarding the inter-relation between economic, marital, and racial/ethnic differences in presentation and survival of surgically resected lung cancer patients. Our investigation will assess these differences in addition to known therapeutic, patient, and histopathologic factors. Methods: A retrospective review of the Surveillance Epidemiology and End Reporting database was conducted through the years 2007-2012. The population was split into nine different ethnic groups. Population differences were assessed via chi-square testing. Multivariable analysis (MVA) were used to detect overall survival (OS) differences in the total surgical population (TS, N = 35,689) in an ear (T1-T2 < 4 cm N0) surgical population [early-stage resectable (ESR), N = 17,931]. Lung cancer-specific survival (LCSS) was assessed in the ESR. Conclusion: In TS and ESR groups, OS was not different in the two largest ethnic groups (Black and Hispanic) as compared to Whites, but was related to single/widowed/divorced status, Medicaid insurance, and income (TS group only). Nodal positivity was associated with patients who did not have a married partner or insurance suggesting that these factors may impact disease biology. Economic and psychosocial variables may play a role in survival of ear lung cancer in addition to standard histopathologic and treatment variables.
- Subjects
NON-small-cell lung carcinoma
- Publication
Frontiers in Oncology, 2018, p1
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2018.00146