We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Real-time 2D/3D registration using kV-MV image pairs for tumor motion tracking in image guided radiotherapy.
- Authors
Furtado, Hugo; Steiner, Elisabeth; Stock, Markus; Georg, Dietmar; Birkfellner, Wolfgang
- Abstract
Intra-fractional respiratory motion during radiotherapy leads to a larger planning target volume (PTV). Real-time tumor motion tracking by two-dimensional (2D)/3D registration using on-board kilo-voltage (kV) imaging can allow for a reduction of the PTV though motion along the imaging beam axis cannot be resolved using only one projection image. We present a retrospective patient study investigating the impact of paired portal mega-voltage (MV) and kV images on registration accuracy. Material and methods. We used data from 10 patients suffering from non-small cell lung cancer (NSCLC) undergoing stereotactic body radiation therapy (SBRT) lung treatment. For each patient we acquired a planning computed tomography (CT) and sequences of kV and MV images during treatment. We compared the accuracy of motion tracking in six degrees-of-freedom (DOF) using the anterior-posterior (AP) kV sequence or the sequence of kV-MV image pairs. Results. Motion along cranial-caudal direction could accurately be extracted when using only the kV sequence but in AP direction we obtained large errors. When using kV-MV pairs, the average error was reduced from 2.9 mm to 1.5 mm and the motion along AP was successfully extracted. Mean registration time was 188 ms. Conclusion. Our evaluation shows that using kV-MV image pairs leads to improved motion extraction in six DOF and is suitable for real-time tumor motion tracking with a conventional LINAC.
- Subjects
RADIOTHERAPY; LUNG cancer; COMPUTERS in medicine; RESEARCH funding; THERAPEUTICS; TOMOGRAPHY; RETROSPECTIVE studies; DESCRIPTIVE statistics
- Publication
Acta Oncologica, 2013, Vol 52, Issue 7, p1464
- ISSN
0284-186X
- Publication type
Article
- DOI
10.3109/0284186X.2013.814152