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- Title
Papel del sistema Purkinje y del tracto de salida del ventrículo derecho en las arritmias ventriculares malignas y la muerte súbita.
- Authors
Dorantes Sánchez, Margarita; Castro Hevia, Jesús A.; Castañeda Chirin, Osmín
- Abstract
The Purkinje system and the right ventricular outflow tract play a pivotal role in relation to malignant ventricular arrhythmias (ventricular tachycardia and fibrill ation, torsades de pointes) and sudden cardiac death. Details such as their path ophysiology, origin involvement (triggering extrasystoles) maintenance of such arrhythmias, and ablative possibilities to reduce recurrences and electrical storm events are disc ussed herein. The differential diagnosis between benign and mali gnant ventricular tachycardia related to the right ventricular outflow tract, and the relationship between genetic, structural, electroanatomical and functional factors (inflammation, fibrosis) with clinical events and vulnerability to arrhythmias are presented. Some of these diseases need to be reclassified as they are now seen in their organic-functional character (Brugada syndrome, for example), and this i mplies radical changes in some class ical concepts as well as a new perspective on risk stratification and therapeutic management.
- Publication
CorSalud, 2020, Vol 12, Issue 1, p77
- ISSN
2078-7170
- Publication type
Article