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Atlas-based methods for efficient characterization of patient-specific ventricular activation patterns.
Published in:
2021
By:
- Vincent, Kevin P;
- Forsch, Nickolas;
- Govil, Sachin;
- Joblon, Jake M;
- Omens, Jeffrey H;
- Perry, James C;
- McCulloch, Andrew D
Publication type:
journal article
Non-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes.
Published in:
2016
By:
- Villongco, Christopher T.;
- Krummen, David E.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
journal article
Mechanical discoordination increases continuously after the onset of left bundle branch block despite constant electrical dyssynchrony in a computational model of cardiac electromechanics and growth.
Published in:
EP: Europace, 2012, v. 14, n. suppl_5, p. v65, doi. 10.1093/europace/eus274
By:
- Kerckhoffs, Roy C.P.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
Article
A Novel Atlas-Based Strategy for Understanding Cardiac Dysfunction in Patients with Congenital Heart Disease.
Published in:
Molecular & Cellular Biomechanics, 2019, v. 16, n. 3, p. 179, doi. 10.32604/mcb.2019.07384
By:
- Salehyar, Sara;
- Forsch, Nickolas;
- Gilbert, Kathleen;
- Young, Alistair A.;
- Perry, James C.;
- Hegde, Sanjeet;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
Article
Systems Modeling of Cardiomyocyte Mechanobiology.
Published in:
Molecular & Cellular Biomechanics, 2019, v. 16, p. 1, doi. 10.32604/mcb.2019.05693
By:
- Tan, Philip M.;
- Buchholz, Kyle S.;
- Shulin Cao;
- Aboelkassem, Yasser;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.;
- Saucerman, Jeffrey J.
Publication type:
Article
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 4, p. 1209, doi. 10.1172/JCI61134
By:
- Sheikh, Farah;
- Kunfu Ouyang;
- Campbell, Stuart G.;
- Lyon, Robert C.;
- Chuang, Joyce;
- Fitzsimons, Dan;
- Tangney, Jared;
- Hidalgo, Carlos G.;
- Chung, Charles S.;
- Hongqiang Cheng;
- Dalton, Nancy D.;
- Yusu Gu;
- Kasahara, Hideko;
- Ghassemian, Majid;
- Omens, Jeffrey H.;
- Peterson, Kirk L.;
- Granzier, Henk L.;
- Moss, Richard L.;
- McCulloch, Andrew D.;
- Ju Chen
Publication type:
Article
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice.
Published in:
2008
By:
- Sheikh, Farah;
- Raskin, Anna;
- Chu, Pao-Hsien;
- Lange, Stephan;
- Domenighetti, Andrea A.;
- Zheng, Ming;
- Liang, Xingqun;
- Zhang, Tong;
- Yajima, Toshitaka;
- Gu, Yusu;
- Dalton, Nancy D.;
- Mahata, Sushil K.;
- Dorn II, Gerald W.;
- Heller-Brown, Joan;
- Peterson, Kirk L.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.;
- Chen, Ju;
- Dorn, Gerald W 2nd;
- Brown, Joan Heller
Publication type:
journal article
Three-Dimensional Micropatterned Cardiac Tissue Cultures.
Published in:
Microscopy & Microanalysis, 2005, v. 11, p. 110, doi. 10.1017/S1431927605509504
By:
- McCulloch, Andrew D.;
- Gallagher, John O.;
- Bhatia, Sangeeta N.;
- Borg, Thomas K.;
- Omens, Jeffrey H.
Publication type:
Article
Biventricular shape modes discriminate pulmonary valve replacement in tetralogy of Fallot better than imaging indices.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28358-w
By:
- Govil, Sachin;
- Mauger, Charlène;
- Hegde, Sanjeet;
- Occleshaw, Christopher J.;
- Yu, Xiaoyang;
- Perry, James C.;
- Young, Alistair A.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
Article
Preventing post-surgical cardiac adhesions with a catechol-functionalized oxime hydrogel.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24104-w
By:
- Fujita, Masaki;
- Policastro, Gina M.;
- Burdick, Austin;
- Lam, Hillary T.;
- Ungerleider, Jessica L.;
- Braden, Rebecca L.;
- Huang, Diane;
- Osborn, Kent G.;
- Omens, Jeffrey H.;
- Madani, Michael M.;
- Christman, Karen L.
Publication type:
Article
Cardiac myocyte force development during differentiation and maturation.
Published in:
Annals of the New York Academy of Sciences, 2010, v. 1188, n. 1, p. 121, doi. 10.1111/j.1749-6632.2009.05091.x
By:
- Jacot, Jeffrey G.;
- Kita‐Matsuo, Hiroko;
- Wei, Karen A.;
- Vincent Chen, H.S.;
- Omens, Jeffrey H.;
- Mercola, Mark;
- McCulloch, Andrew D.
Publication type:
Article
Discovering Regulators of the Drosophila Cardiac Hypoxia Response Using Automated Phenotyping Technology.
Published in:
Annals of the New York Academy of Sciences, 2008, v. 1123, p. 169, doi. 10.1196/annals.1420.019
By:
- Feala, Jacob D.;
- Omens, Jeffrey H.;
- Paternostro, Giovanni;
- McCulloch, Andrew D.
Publication type:
Article
Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers.
Published in:
Biotechnology & Bioengineering, 2003, v. 81, n. 5, p. 578, doi. 10.1002/bit.10506
By:
- Gopalan, Sindhu M.;
- Flaim, Chris;
- Bhatia, Sangeeta N.;
- Hoshijima, Masahiko;
- Knoell, Ralph;
- Chien, Kenneth R.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
Article
Increased Infarct Wall Thickness by a Bio-Inert Material Is Insufficient to Prevent Negative Left Ventricular Remodeling after Myocardial Infarction.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021571
By:
- Rane, Aboli A.;
- Chuang, Joyce S.;
- Shah, Amul;
- Hu, Diane P.;
- Dalton, Nancy D.;
- Gu, Yusu;
- Peterson, Kirk L.;
- Omens, Jeffrey H.;
- Christman, Karen L.
Publication type:
Article
Modifying Ventricular Fibrillation by Targeted Rotor Substrate Ablation: Proof-of-Concept from Experimental Studies to Clinical VF.
Published in:
Journal of Cardiovascular Electrophysiology, 2015, v. 26, n. 10, p. 1117, doi. 10.1111/jce.12753
By:
- KRUMMEN, DAVID E.;
- HAYASE, JUSTIN;
- VAMPOLA, STEPHEN P.;
- HO, GORDON;
- SCHRICKER, AMIR A.;
- LALANI, GAUTAM G.;
- BAYKANER, TINA;
- COE, TAYLOR M.;
- CLOPTON, PAUL;
- RAPPEL, WOUTER‐JAN;
- OMENS, JEFFREY H.;
- NARAYAN, SANJIV M.
Publication type:
Article
Ventricular Filling Slows Epicardial Conduction and Increases Action Potential Duration in an Optical Mapping Study of the Isolated Rabbit Heart.
Published in:
Journal of Cardiovascular Electrophysiology, 2003, v. 14, n. 7, p. 739, doi. 10.1046/j.1540-8167.2003.03072.x
By:
- Sung, Derrick;
- Mills, Robert W.;
- Schettler, Jan;
- Narayan, Sanjiv M.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
Article
Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling
Published in:
Cardiovascular Research, 2005, v. 67, n. 1, p. 106, doi. 10.1016/j.cardiores.2005.02.016
By:
- Gurantz, Devorah;
- Yndestad, Arne;
- Halvorsen, Bente;
- Lunde, Ottar V.;
- Omens, Jeffrey H.;
- Ueland, Thor;
- Aukrust, Pål;
- Moore, Cristina D.;
- Kjekshus, John;
- Greenberg, Barry H.
Publication type:
Article
Structural basis of regional dysfunction in acutely ischemic myocardium.
Published in:
Cardiovascular Research, 2000, v. 47, n. 2, p. 284, doi. 10.1016/S0008-6363(00)00089-4
By:
- Mazhari, Reza;
- Omens, Jeffrey H;
- Covell, James W;
- McCulloch, Andrew D
Publication type:
Article
Predictions of hypertrophy and its regression in response to pressure overload.
Published in:
Biomechanics & Modeling in Mechanobiology, 2020, v. 19, n. 3, p. 1079, doi. 10.1007/s10237-019-01271-w
By:
- Yoshida, Kyoko;
- McCulloch, Andrew D.;
- Omens, Jeffrey H.;
- Holmes, Jeffrey W.
Publication type:
Article
High-order finite element methods for cardiac monodomain simulations.
Published in:
Frontiers in Physiology, 2015, p. 1, doi. 10.3389/fphys.2015.00217
By:
- Vincent, Kevin P.;
- Gonzales, Matthew J.;
- Gillette, Andrew K.;
- Villongco, Christopher T.;
- Pezzuto, Simone;
- Omens, Jeffrey H.;
- Holst, Michael J.;
- McCulloch, Andrew D.
Publication type:
Article
Flow–function relations during graded coronary occlusions in the dog: effects of transmural location and segment orientation.
Published in:
Cardiovascular Research, 1998, v. 37, n. 3, p. 636, doi. 10.1016/S0008-6363(97)00290-3
By:
- McCulloch, Andrew D;
- Sung, Derrick;
- Wilson, James M;
- Pavelec, Richard S;
- Omens, Jeffrey H
Publication type:
Article
Relationship between passive tissue strain and collagen uncoiling during healing of infarcted myocardium.
Published in:
Cardiovascular Research, 1997, v. 33, n. 2, p. 351, doi. 10.1016/S0008-6363(96)00206-4
By:
- Omens, Jeffrey H;
- Miller, Timothy R;
- Covell, James W
Publication type:
Article
Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 5, p. 1134, doi. 10.1093/hmg/ddt508
By:
- Lyon, Robert C.;
- Mezzano, Valeria;
- Wright, Adam T.;
- Pfeiffer, Emily;
- Chuang, Joyce;
- Banares, Katherine;
- Castaneda, Allan;
- Ouyang, Kunfu;
- Cui, Li;
- Contu, Riccardo;
- Gu, Yusu;
- Evans, Sylvia M.;
- Omens, Jeffrey H.;
- Peterson, Kirk L.;
- McCulloch, Andrew D.;
- Sheikh, Farah
Publication type:
Article
Early postmyocardial infarction survival in Murphy Roths Large mice is mediated by attenuated apoptosis and inflammation but depends on genetic background.
Published in:
Experimental Physiology, 2012, v. 97, n. 1, p. 102, doi. 10.1113/expphysiol.2011.060269
By:
- Hunt, Darlene L.;
- Campbell, Patrick H.;
- Zambon, Alexander C.;
- Vranizan, Karen;
- Evans, Sylvia M.;
- Kuo, Hai-Chien;
- Yamaguchi, Ken D.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.
Publication type:
Article
Effect of transmurally heterogeneous myocyte excitation–contraction coupling on canine left ventricular electromechanics.
Published in:
Experimental Physiology, 2009, v. 94, n. 5, p. 541, doi. 10.1113/expphysiol.2008.044057
By:
- Campbell, Stuart G.;
- Howard, Elliot;
- Aguado-Sierra, Jazmin;
- Coppola, Benjamin A.;
- Omens, Jeffrey H.;
- Mulligan, Lawrence J.;
- McCulloch, Andrew D.;
- P. Kerckhoffs, Roy C.
Publication type:
Article
Successful cardiac resynchronization therapy reduces negative septal work in patient-specific models of dyssynchronous heart failure.
Published in:
PLoS Computational Biology, 2024, v. 20, n. 10, p. 1, doi. 10.1371/journal.pcbi.1012150
By:
- Craine, Amanda;
- Krishnamurthy, Adarsh;
- Villongco, Christopher T.;
- Vincent, Kevin;
- Krummen, David E.;
- Narayan, Sanjiv M.;
- Kerckhoffs, Roy C. P.;
- Omens, Jeffrey H.;
- Contijoch, Francisco;
- McCulloch, Andrew D.
Publication type:
Article
Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI.
Published in:
Magnetic Resonance in Medicine, 2010, v. 64, n. 5, p. 1281, doi. 10.1002/mrm.22547
By:
- Chuang, Joyce S.;
- Zemljic-Harpf, Alice;
- Ross, Robert S.;
- Frank, Lawrence R.;
- McCulloch, Andrew D.;
- Omens, Jeffrey H.
Publication type:
Article
High-resolution longitudinal MRI of the transition to heart failure.
Published in:
Magnetic Resonance in Medicine, 2007, v. 57, n. 4, p. 714, doi. 10.1002/mrm.21182
By:
- Costandi, Peter N.;
- McCulloch, Andrew D.;
- Omens, Jeffrey H.;
- Frank, Lawrence R.
Publication type:
Article
Decreasing Compensatory Ability of Concentric Ventricular Hypertrophy in Aortic-Banded Rat Hearts.
Published in:
Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00037
By:
- Lewalle, Alexandre;
- Land, Sander;
- Carruth, Eric;
- Frank, Lawrence R.;
- Lamata, Pablo;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.;
- Niederer, Steven A.;
- Smith, Nicolas P.
Publication type:
Article
Predictive model identifies key network regulators of cardiomyocyte mechano-signaling.
Published in:
PLoS Computational Biology, 2017, v. 13, n. 11, p. 1, doi. 10.1371/journal.pcbi.1005854
By:
- Tan, Philip M.;
- Buchholz, Kyle S.;
- Omens, Jeffrey H.;
- McCulloch, Andrew D.;
- Saucerman, Jeffrey J.
Publication type:
Article

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