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Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 2, p. 196, doi. 10.1165/rcmb.2021-0358OC
By:
- Russell, Clark D.;
- Valanciute, Asta;
- Gachanja, Naomi N.;
- Stephen, Jillian;
- Penrice-Randal, Rebekah;
- Armstrong, Stuart D.;
- Clohisey, Sara;
- Bo Wang;
- Al Qsous, Wael;
- Wallace, William A.;
- Oniscu, Gabriel C.;
- Stevens, Jo;
- Harrison, David J.;
- Dhaliwal, Kevin;
- Hiscox, Julian A.;
- Baillie, J. Kenneth;
- Akram, Ahsan R.;
- Dorward, David A.;
- Lucas, Christopher D.
Publication type:
Article
Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury.
Published in:
Journal of Inflammation, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12950-020-00261-5
By:
- Macfarlane, James G.;
- Dorward, David A.;
- Ruchaud-Sparagano, Marie-Hélène;
- Scott, Jonathan;
- Lucas, Christopher D.;
- Rossi, Adriano G.;
- Simpson, A. John
Publication type:
Article
Flavones induce neutrophil apoptosis by downregulation of Mcl-1 via a proteasomal-dependent pathway.
Published in:
FASEB Journal, 2013, v. 27, n. 3, p. 1084, doi. 10.1096/fj.12-218990
By:
- Lucas, Christopher D.;
- Allen, Keith C.;
- Dorward, David A.;
- Hoodless, Laura J.;
- Melrose, Lauren A.;
- Marwick, John A.;
- Tucker, Carl S.;
- Haslett, Christopher;
- Duffin, Rodger;
- Rossi, Adriano G.
Publication type:
Article
Thrombosis Imaging in Patients Recovering from COVID-19 and Pulmonary Embolism.
Published in:
2021
By:
- Bing, Rong;
- Andrews, Jack P. M.;
- Williams, Michelle C.;
- van Beek, Edwin J. R.;
- Lucatelli, Christophe;
- MacNaught, Gillian;
- Clark, Tim;
- Koglin, Norman;
- Stephens, Andrew W.;
- MacAskill, Mark G.;
- Tavares, Adriana A. S.;
- Dhaliwal, Kevin;
- Dorward, David A.;
- Lucas, Christopher D.;
- Dweck, Marc R.;
- Newby, David E.;
- Andrews, Jack Pm;
- Tavares, Adriana As;
- Lucas, Christopher
Publication type:
journal article
Apoptotic cell clearance: basic biology and therapeutic potential.
Published in:
Nature Reviews Immunology, 2014, v. 14, n. 3, p. 166, doi. 10.1038/nri3607
By:
- Poon, Ivan K. H.;
- Lucas, Christopher D.;
- Rossi, Adriano G.;
- Ravichandran, Kodi S.
Publication type:
Article
Pannexin 1 drives efficient epithelial repair after tissue injury.
Published in:
Science Immunology, 2022, v. 7, n. 71, p. 1, doi. 10.1126/sciimmunol.abm4032
By:
- Lucas, Christopher D.;
- Medina, Christopher B.;
- Bruton, Finnius A.;
- Dorward, David A.;
- Raymond, Michael H.;
- Tufan, Turan;
- Etchegaray, J. Iker;
- Barron, Brady;
- Oremek, Magdalena E. M.;
- Arandjelovic, Sanja;
- Farber, Emily;
- Onngut-Gumuscu, Suna;
- Ke, Eugene;
- Whyte, Moira K. B.;
- Rossi, Adriano G.;
- Ravichandran, Kodi S.
Publication type:
Article
Epithelial Cells and Inflammation in Pulmonary Wound Repair.
Published in:
Cells (2073-4409), 2021, v. 10, n. 2, p. 339, doi. 10.3390/cells10020339
By:
- Croasdell Lucchini, Amanda;
- Gachanja, Naomi N.;
- Rossi, Adriano G.;
- Dorward, David A.;
- Lucas, Christopher D.;
- Filep, János G.
Publication type:
Article
Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps.
Published in:
Journal of Inflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1476-9255-10-12
By:
- Gray, Robert D.;
- Lucas, Christopher D.;
- MacKellar, Annie;
- Feng Li;
- Hiersemenzel, Katia;
- Haslett, Chris;
- Davidson, Donald J.;
- Rossi, Adriano G.
Publication type:
Article
Post-mortem dissection of COVID-19: a pathogenic role for macrophages?
Published in:
Intensive Care Medicine, 2021, v. 47, n. 11, p. 1322, doi. 10.1007/s00134-021-06509-9
By:
- Velu, Prasad P.;
- Lucas, Christopher D.;
- Conway Morris, Andrew
Publication type:
Article
Non-small-cell lung carcinoma (not otherwise specified) rates are not influenced solely by pathologists' decisions on the use of immunohistochemistry.
Published in:
Histopathology, 2017, v. 70, n. 3, p. 500, doi. 10.1111/his.13074
By:
- Chapman, Gavin B;
- Dorward, David A;
- Lucas, Christopher D;
- Wallace, William A
Publication type:
Article
ARAP3 protects from excessive formylated peptide‐induced microvascular leakage by acting on endothelial cells and neutrophils.
Published in:
Journal of Pathology, 2024, v. 263, n. 3, p. 347, doi. 10.1002/path.6288
By:
- Chu, Julia Y;
- McCormick, Barry;
- Sundaram, Kruthika;
- Hardisty, Gareth;
- Karmakar, Utsa;
- Pumpe, Caroline;
- Krull, Elizabeth;
- Lucas, Christopher D;
- Amado‐Azevedo, Joana;
- Hordijk, Peter L;
- Caporali, Andrea;
- Mellor, Harry;
- Baillie, J Kenneth;
- Rossi, Adriano G;
- Vermeren, Sonja
Publication type:
Article
Neutrophils in the initiation and resolution of acute pulmonary inflammation: understanding biological function and therapeutic potential.
Published in:
Journal of Pathology, 2019, v. 247, n. 5, p. 672, doi. 10.1002/path.5221
By:
- Potey, Philippe MD;
- Rossi, Adriano G;
- Lucas, Christopher D;
- Dorward, David A
Publication type:
Article
Wogonin Induces Eosinophil Apoptosis and Attenuates Allergic Airway Inflammation.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 6, p. 626, doi. 10.1164/rccm.201408-1565OC
By:
- Lucas, Christopher D.;
- Dorward, David A.;
- Sharma, Sidharth;
- Rennie, Jillian;
- Felton, Jennifer M.;
- Alessandri, Ana L.;
- Duffin, Rodger;
- Schwarze, Jurgen;
- Haslett, Christopher;
- Rossi, Adriano G.
Publication type:
Article
Histological Evidence of Pulmonary Microthrombosis and Vasculitis in Life-Threatening Respiratory Virus Diseases.
Published in:
Open Forum Infectious Diseases, 2021, v. 8, n. 2, p. 1, doi. 10.1093/ofid/ofaa640
By:
- Dolby, Heather W;
- Potey, Philippe;
- Wilder-Smith, Annika B;
- Clohisey, Sara;
- Millar, Jonathan E;
- Baillie, J Kenneth;
- Dorward, David A;
- Lucas, Christopher D;
- Russell, Clark D
Publication type:
Article
Induction of Eosinophil Apoptosis by the Cyclin- Dependent Kinase Inhibitor AT7519 Promotes the Resolution of Eosinophil-Dominant Allergic Inflammation.
Published in:
PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025683
By:
- Alessandri, Ana L.;
- Duffin, Rodger;
- Leitch, Andrew E.;
- Lucas, Christopher D.;
- Sheldrake, Tara A.;
- Dorward, David A.;
- Hirani, Nik;
- Pinho, Vanessa;
- Sousa, Lirlândia Pires de;
- Teixeira, Mauro M.;
- Lyons, John F.;
- Haslett, Christopher;
- Rossi, Adriano G.
Publication type:
Article
Inflammation Resolution and the Induction of Granulocyte Apoptosis by Cyclin-Dependent Kinase Inhibitor Drugs.
Published in:
Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00055
By:
- Cartwright, Jennifer A.;
- Lucas, Christopher D.;
- Rossi, Adriano G.
Publication type:
Article
Swimming Against the Tide: Drugs Drive Neutrophil Reverse Migration.
Published in:
Science Translational Medicine, 2014, v. 6, n. 225, p. 1, doi. 10.1126/scitranslmed.3008666
By:
- Lucas, Christopher D.;
- Hoodless, Laura J.;
- Rossi, Adriano G.
Publication type:
Article
Intestinal Protein Characterisation of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in Inflammatory Bowel Disease (IBD) and Fatal COVID-19 Infection.
Published in:
Inflammation, 2022, v. 45, n. 2, p. 567, doi. 10.1007/s10753-021-01567-z
By:
- McAllister, Milly J.;
- Kirkwood, Kathryn;
- Chuah, Shaun C.;
- Thompson, Emily J.;
- Cartwright, Jennifer A.;
- Russell, Clark D.;
- Dorward, David A.;
- Lucas, Christopher D.;
- Ho, Gwo-tzer
Publication type:
Article
Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo.
Published in:
Scientific Reports, 2016, p. 36980, doi. 10.1038/srep36980
By:
- Hoodless, Laura J.;
- Lucas, Christopher D.;
- Duffin, Rodger;
- Denvir, Martin A.;
- Haslett, Christopher;
- Tucker, Carl S.;
- Rossi, Adriano G.
Publication type:
Article

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