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- Title
Old Age and Outcome After Primary Angioplasty for Acute Myocardial Infarction.
- Authors
de Boer, Menko-Jan; Ottervanger, Jan Paul; Suryapranata, Harry; Hoorntje, Jan C.A.; Dambrink, Jan-Henk E.; Gosselink, A.T. Marcel; van't Hof, Arnoud W.J.; Zijlstra, Felix
- Abstract
OBJECTIVES: To assess the influence of age as an independent factor determining the prognosis and outcome of patients with acute myocardial infarction (AMI) treated using primary percutaneous coronary intervention (PCI). DESIGN: A retrospective analysis from a dedicated database. SETTING: A high-volume interventional cardiology center in the Netherlands. PARTICIPANTS: Four thousand nine hundred thirty-three consecutive patients with AMI. MEASUREMENTS: Baseline characteristics and clinical outcomes after 30 days and 1 year were compared according to age categorized in three groups: younger than 65, 65 to 74, and 75 and older. A more-detailed analysis was performed with six age groups, from younger than 40 to 80 and older. RESULTS: Of the 4,933 consecutive patients with AMI treated with PCI between 1992 and 2004, 643 were aged 75 and older. Multivariate analysis revealed that patients aged 65 to 75 had a greater risk of 1-year mortality than those younger than 65 (adjusted odds ratio (AOR)=1.57, 95% confidence interval (CI)=1.15–2.16) and that those aged 75 and older had a greater risk of 1-year mortality than those younger than 65 (AOR=3.03, 95% CI=2.14–4.29). CONCLUSION: In this retrospective analysis, older age was independently associated with greater mortality after PCI for AMI. Patients aged 65 and older had a higher risk of mortality than younger patients, and those aged 75 and older had the highest risk of mortality.
- Subjects
MYOCARDIAL infarction; PROGNOSIS; ANGIOPLASTY; OLDER patients; PATIENTS
- Publication
Journal of the American Geriatrics Society, 2010, Vol 58, Issue 5, p867
- ISSN
0002-8614
- Publication type
Article
- DOI
10.1111/j.1532-5415.2010.02821.x