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- Title
Extensive surgery for carcinoma of the gallbladder.
- Authors
Kondo, S; Nimura, Y; Hayakawa, N; Kamiya, J; Nagino, M; Uesaka, K
- Abstract
Background: The purpose of this study was to clarify the efficacy of, and define the indications for, extensive surgery for gallbladder carcinoma. Methods: Between 1979 and 1994, 116 patients with gallbladder carcinoma underwent operation. Radical resection was performed in 80 patients. Results: In 68 patients with stage III or IV disease, extensive resection including extended right hepatectomy (n = 40), pancreaticoduodenectomy (n = 23) and/or portal vein resection (n = 23) was employed to achieve complete tumour excision. The hospital mortality rate was 18 per cent. The postoperative 3- and 5-year survival rates were 44 and 33 per cent respectively in the patients with stage III disease (n = 9), and 24 and 17 per cent respectively in patients with stage IV (M0 ) disease (n = 29). In contrast, the postoperative survival rate for the 30 patients with stage IV (M1 ) disease (7 per cent at 3 years and 3 per cent at 5 years) was worse than that for patients with stage III and stage IV (M0 ) disease (P = 0·009 and P = 0·062 respectively). Conclusion: Radical resection should be undertaken for stage III and stage IV (M0 ) gallbladder cancer. Although portal vein resection and/or pancreaticoduodenectomy did not contribute to long-term survival, better survival was obtained than that for the unresected patients.
- Subjects
GALLBLADDER cancer; ADJUVANT treatment of cancer
- Publication
British Journal of Surgery, 2002, Vol 89, Issue 2, p179
- ISSN
0007-1323
- Publication type
Article
- DOI
10.1046/j.0007-1323.2001.02001.x