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- Title
The Effect of Manuka Honey on the Structure of Bacteria.
- Authors
Cooper, R. A.; Henriques, A. F. M.; Burton, N. F.
- Abstract
BACKGROUND Although Manuka honey has been shown to be bactericidal for bacteria, the mechanism of inhibition has not been elucidated. METHODS Using cultures of Staphylococcus aureus and Pseudomonas aeruginosa the MIC and MBC values of Manuka honey were established. Using concentrations of Manuka honey two or three times higher than MICs, cultures were incubated with and without honey for 4 or 8 hours and examined using electron microscopy. RESULTS Both scanning and transmission electron microscopy were used. Structural changes in Staphylococcus aureus were distinct from those observed in Pseudomonas aeruginosa. CONCLUSIONS This suggests that Manuka honey has different target sites in these two bacteria.
- Subjects
HONEY; BACTERIA; STAPHYLOCOCCUS aureus; PSEUDOMONAS aeruginosa; SCANNING electron microscopy; TRANSMISSION electron microscopy
- Publication
Malaysian Journal of Medical Sciences, 2007, Vol 14, Issue 1, p108
- ISSN
1394-195X
- Publication type
Article