The article presents a study that examines the Kapisi's sarcoman-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA) protein which is responsible for the hitchhiking activity. They used purification and mass spectrometry to look for potential protein binding partners for LANA. However, the team showed that LANA bound to histones H2A and H2B rather than H3 and H4. Moreover, the N-terminal region of LANA is required for chromosome association.