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- Title
Ionic Liquid 3-Methyl-1-sulphonic Acid Imidazolium Chloride {[Msim]Cl}: A Highly Efficient, Mild and Green Catalyst for the Synthesis of β-Acetamido Ketones.
- Authors
Zare, Abdolkarim; Hekmat-Zadeh, Tahereh; Mirzaei-Monfared, Setareh; Merajoddin, Maria; Torabi-Monfared, Hossein; Zolfigol, Mohammad Ali; Moosavi-Zare, Ahmad Reza; Rostami, Esmael; Mokhlesi, Mohammad; Derakhshan-Panah, Fatemeh; Porbahi, Saeedeh; Balandeh, Samira
- Abstract
Brønstedacidic ionic liquid 3-methyl-1-sulphonic acid imidazoliumchloride {[Msim]Cl} is utilized as ahighly efficient, inexpensive, mild and green catalyst for the synthesis of β-acetamido ketones by the one-pot multi-component coupling between acetophenones, arylaldehydes, acetonitrile and acetyl chloride at roomtemperature. Under these conditions, the title compounds are produced in high to excellent yields and in relatively short reaction times. In addition, this method is superior to reported methods, for the synthesis of β-acetamido ketones and is applicable for the synthesis of tris(β-acetamido ketone).
- Subjects
IONIC liquids; IMIDAZOLES; CATALYSTS; KETONES; ACETONITRILE
- Publication
South African Journal of Chemistry, 2012, Vol 65, p63
- ISSN
0379-4350
- Publication type
Article