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- Title
Long-term characterization of persistent atrial fibrillation: wave morphology, frequency, and irregularity analysis.
- Authors
Goya-Esteban, Rebeca; Sandberg, Frida; Barquero-Pérez, Óscar; García-Alberola, Arcadio; Sörnmo, Leif; Rojo-Álvarez, José
- Abstract
Short-term properties of atrial fibrillation (AF) frequency, f-wave morphology, and irregularity parameters have been thoroughly studied, but not long-term properties. In the present work, f-wave morphology is characterized by principal component analysis, introducing a novel temporal parameter defined by the cumulative normalized variance of the three largest principal components $$(r_3)$$ . Based on 7-day recordings from nine patients with stable chronic heart failure and persistent AF, long-term properties were studied in terms of $$r_3$$ , AF frequency, and sample entropy $$(SampEn)$$ . The main result of the present study is that detection of circadian rhythms depends on the parameter considered: rhythms were found in six $$(r_3, SampEn)$$ and five (AF frequency) patients, but not always in the same patient. Another important result is that circadian rhythms detected in 7-day recordings could not always be detected in 24-h periods, thus shedding new light on the results in previous studies which all were based on 24-h recordings. Infradian rhythms were found in four $$(r_3, SampEn)$$ and one (AF frequency) patients.
- Subjects
ATRIAL fibrillation; HEART failure patients; CIRCADIAN rhythms; HEART physiology; PRINCIPAL components analysis
- Publication
Medical & Biological Engineering & Computing, 2014, Vol 52, Issue 12, p1053
- ISSN
0140-0118
- Publication type
Article
- DOI
10.1007/s11517-014-1199-x