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- Title
Motion‐tolerant diffusion mapping based on single‐shot overlapping‐echo detachment (OLED) planar imaging.
- Authors
Ma, Lingceng; Cai, Congbo; Yang, Hongyi; Cai, Shuhui; Qian, Junchao; Xiao, Lizhi; Zhong, Kai; Chen, Zhong
- Abstract
Purpose: A new diffusion‐mapping method based on single‐shot overlapping‐echo detachment (DM‐OLED) planar‐imaging sequence, along with a corresponding separation algorithm, is proposed to achieve reliable quantitative diffusion mapping in a single shot. The method can resist the effects of motion and help in detecting the quick variation of diffusion under different physiological status. Methods: The echo‐planar imaging method is combined with two excitation pulses with small flip angle to gain overlapping‐echo signal in a single shot. Then the overlapping signals are separated by a separation algorithm and used for diffusion computation. Numerical simulation, phantom, and in vivo rat experiments were performed to verify the efficiency, accuracy, and motion tolerance of DM‐OLED. Results: The DM‐OLED sequence could obtain reliable diffusion maps within milliseconds in numerical simulation, phantom, and in vivo experiments. Compared with conventional diffusion mapping with spin‐echo echo‐planar imaging, DM‐OLED has higher time resolution and fewer motion‐incurred errors in the apparent diffusion coefficient maps. Conclusions: As a reliable fast diffusion measurement tool, DM‐OLED shows promise for real‐time dynamic diffusion mapping and functional magnetic resonance imaging. Magn Reson Med 80:200–210, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
- Publication
Magnetic Resonance in Medicine, 2018, Vol 80, Issue 1, p200
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.27023