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- Title
Effect of the Molecular Mass of Tremella Polysaccharides on Accelerated Recovery from Cyclophosphamide-Induced Leucopenia in Rats.
- Authors
Rui-Zhi Jiang; Ying Wang; Hao-Ming Luo; Yan-Qiu Cheng; Ying-Hong Chen; Yang Gao; Qi-Pin Gao
- Abstract
The body of tremella were decocted with water, and hydrolyzed with 0.1 mol/L hydrochloric acid for different times, giving tremella polysaccharides with six molecular mass values. The structures of all the tremella polysaccharides had non-reducing terminals of β-D-pyranglucuronide, the backbone was composed of (1→3)-linked β-D-mannopyranoside, and the side chain composed of (1→6)-linked β-D-xylopyranoside was attached to the C2 of the backbone mannopyranoside. Immunomodulatory effect studies indicated that tremella polysaccharides increased the counts of leukocytes in the peripheral blood which were significantly lowered by cyclophosphamide, and the lower the molecular mass of the tremella polysaccharide, the better this effect was.
- Subjects
POLYSACCHARIDES; TREMELLA; HYDROLYSIS; HYDROCHLORIC acid; MANNOPYRANOSIDE
- Publication
Molecules, 2012, Vol 17, Issue 4, p3609
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules17043609