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- Title
Ultrasound-guided embryo transfer and the accuracy of trial embryo transfer.
- Authors
Mousa I. Shamonki; Steven D. Spandorfer; Zev Rosenwaks
- Abstract
BACKGROUND: Studies have suggested that ultrasound-guided embryo transfer (UG-ET) may improve the outcome in IVF; however, several factors may account for the improvement in pregnancy rate. This study examines the use of ultrasound to determine the accuracy of trial transfer (TT) in preparation for ET. METHODS: Sixty-seven consecutive patients prospectively underwent UG-ET over a 2 month period. Total cavity length by US was compared with the length noted by TT. A difference of =1?cm was considered significant. All embryos were placed within 12?cm of the fundus by US. RESULTS: Twenty patients (29.9%) had a difference of =1?cm and 13 patients (19.4%) had a difference of =1.5?cm. Patients with a difference of =1 or =1.5?cm had a significantly greater depth at transfer (P<0.001) and uterine cavity length (P<0.001) when compared with patients without a difference. Clinical pregnancy, implantation, delivery and overall miscarriage rates did not differ between patients with a difference of =1 or =1.5?cm versus no difference. There were no ectopic pregnancies. CONCLUSIONS: Nineteen percent of patients had a discrepancy of =1.5?cm and ~30% had a difference of =1?cm from TT at UG-ET, suggesting a benefit to UG-ET. A large prospective randomized trial comparing UG-ET with blind transfer is required to assess further if UG-ET should be used in all cases of ET.
- Subjects
PREGNANCY complications; CONCEPTION; ECTOPIC pregnancy; EMBRYOLOGY
- Publication
Human Reproduction, 2005, Vol 20, Issue 3, p709
- ISSN
0268-1161
- Publication type
Article
- DOI
10.1093/humrep/deh546