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- Title
Ovarian stimulation and endometrial receptivity.
- Authors
Valbuena, Diana; Jasper, Melinda; Remohí, José; Pellicer, Antonio; Simón, Carlos
- Abstract
Endometrial receptivity is a limiting step in the success of in-vitro fertilization (IVF). To investigate this issue, we selected a specific population of high responder patients in whom implantation was impaired, even when good quality embryos were transferred. We present a series of studies showing that high oestradiol concentrations on the day of human chorionic gonadotrophin (HCG) administration are detrimental to uterine receptivity. In addition, we suggest clinical strategies to improve endometrial receptivity in high responder patients using a step-down regimen.
- Publication
Human Reproduction, 1999, Vol 14, Issue suppl_2, p107
- ISSN
0268-1161
- Publication type
Article
- DOI
10.1093/humrep/14.suppl_2.107