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- Title
Encoding asymmetry within neural circuits.
- Authors
Concha ML; Bianco IH; Wilson SW; Concha, Miguel L; Bianco, Isaac H; Wilson, Stephen W
- Abstract
Genetic and environmental factors control morphological and functional differences between the two sides of the nervous system. Neural asymmetries are proposed to have important roles in circuit physiology, cognition and species-specific behaviours. We propose two fundamentally different mechanisms for encoding left-right asymmetry in neural circuits. In the first, asymmetric circuits share common components; in the second, there are unique unilateral structures. Research in both vertebrates and invertebrates is helping to reveal the mechanisms underlying the development of neural lateralization, but less is known about the function of circuit asymmetries. Technical advances in the coming years are likely to revolutionize our understanding of left-right asymmetry in the nervous system.
- Publication
Nature Reviews Neuroscience, 2012, Vol 13, Issue 11, p832
- ISSN
1471-003X
- Publication type
journal article
- DOI
10.1038/nrn3371