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- Title
Location, location, location — a matter of life and death.
- Authors
Wiedemann, Claudia
- Abstract
The article investigates the influence of the location of N-methyl-d-aspartate receptors (NMDARs) on cellular processes. Previous studies have showed that the activation of NMDARs promote either survival or cell death. In this study, the researchers provide evidence that the location of NMDARs is crucial and that upon receptor activation, specific gene expression programs guide survival or death.
- Subjects
METHYL aspartate; CELLULAR control mechanisms; NEUROTRANSMITTER receptors; GENE expression; CELL metabolism; MOLECULAR genetics
- Publication
Nature Reviews Neuroscience, 2007, Vol 8, Issue 4, p249
- ISSN
1471-003X
- Publication type
Article
- DOI
10.1038/nrn2126