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- Title
Neuropsychological functioning in childhood-onset psychosis and attention-deficit/hyperactivity disorder.
- Authors
Brodsky, Kimberly; Willcutt, Erik G.; Davalos, Deana B.; Ross, Randal G.
- Abstract
Background: Attention-deficit/hyperactivity disorder (ADHD) and childhood-onset psychosis (COP) are chronic, heterogeneous disorders with symptoms that frequently co-occur, but the etiology of their comorbidity is unknown. Studies of each disorder indicate that both ADHD and COP are associated with a range of neuropsychological weaknesses, but few neuropsychological studies have directly compared groups with ADHD and COP. Methods: Groups with ADHD only (32 F, 48 M), COP only (5 F, 5 M), ADHD + COP (9 F, 21 M), and a control group with neither disorder (25 F, 44 M) completed a neuropsychological battery that included measures of verbal working memory, response inhibition, response speed and variability, and selective attention. Results: All three clinical groups exhibited significantly lower performance versus the control group on all neuropsychological measures, whereas the only significant difference between the clinical groups was a significantly larger weakness in verbal working memory in the groups with COP. Conclusions: The frequent co-occurrence between COP and ADHD may reflect shared neuropsychological weaknesses that are most pronounced on measures of working memory and response variability.
- Subjects
ANALYSIS of variance; ATTENTION-deficit hyperactivity disorder; COGNITIVE testing; NEUROPSYCHOLOGICAL tests; PSYCHOLOGICAL tests; PSYCHOSES in children; RESEARCH funding; COMORBIDITY; MULTIPLE regression analysis; CASE-control method; DESCRIPTIVE statistics; CHILDREN
- Publication
Journal of Child Psychology, 2014, Vol 55, Issue 7, p811
- ISSN
0021-9630
- Publication type
Article
- DOI
10.1111/jcpp.12199