We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Structural investigation of endoglucanase 2 from the filamentous fungus Penicillium verruculosum.
- Authors
Vakhrusheva, A.; Nemashkalov, V.; Kravchenko, O.; Tishchenko, S.; Gabdulkhakov, A.; Kljashtorny, V.; Korotkova, O.; Gusakov, A.; Sinitsyn, A.
- Abstract
Enzyme additives capable of degrading non-starch polysaccharides of cereal cell walls, which are major ingredients used in animal feed, can improve the efficiency of livestock production. Non-starch polysaccharides have antinutritional properties that interfere with efficient digestion and assimilation of nutrients by animals. Therefore, the improvement of the properties and characteristics of enzyme additive is an important issue. The three-dimensional structure of one of the key industrial enzymes involved in the degradation of non-starch polysaccharides - endoglucanase 2 from the filamentous fungus Penicillium verruculosum - was determined (PDB ID: 5I6S). The catalytic site of this enzyme was established. Based on the enzyme structure, it was suggested that the pH optimum of the enzyme activity can be shifted from acidic to neutral or alkaline pH values.
- Subjects
ENZYMES; POLYSACCHARIDES; PENICILLIN; BETA lactam antibiotics; ANTIBACTERIAL agents
- Publication
Crystallography Reports, 2017, Vol 62, Issue 2, p254
- ISSN
1063-7745
- Publication type
Article
- DOI
10.1134/S1063774517020304