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- Title
A Meta-Analysis on the Relations between EGFR R521K Polymorphism and Risk of Cancer.
- Authors
Yinsheng Wang; Lidan Zha; Dan Liao; Xiaozhi Li
- Abstract
The EGFR R521K polymorphism has been shown to reduce the activity of EGFR; however, the association between EGFR R521K polymorphism and the risk of cancer remains inconclusive; therefore we performed a meta-analysis to evaluate the relationship between EGFR R521K polymorphism and susceptibility to cancer. Our results suggest that the EGFR R521K polymorphism is not associated with risk of cancer, but the different chemosensitivity to anticancer drugs may need further investigation
- Subjects
EPIDERMAL growth factor receptors; CANCER risk factors; GENETIC polymorphisms; DISEASE susceptibility; ANTINEOPLASTIC agents; ONCOLOGY
- Publication
International Journal of Genomics, 2014, p1
- ISSN
2314-436X
- Publication type
Article
- DOI
10.1155/2014/312102