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- Title
Mild COVID-19 has no detrimental effect on semen quality.
- Authors
Edimiris, Philippos; Doehmen, Cornelius; Müller, Lisa; Andrée, Marcel; Baston-Buest, Dunja Maria; Buest, Sebastian; Adams, Ortwin; Krüssel, Jan-Steffen; Bielfeld, Alexandra Petra
- Abstract
Background: As of today, the effect of coronavirus disease 2019 (COVID-19) on male fertility remains unclear. Studies published so far have partly contradictory results, likely due to very small sample sizes and heterogeneous populations. To gain a deeper understanding of the impact of COVID-19 on male fertility, we performed a prospective case–control study, in which we examined the ejaculate of 37 subjects, including 25 subjects in the acute phase of mild COVID-19 and 12 subjects who did not suffer from COVID-19. Determination of semen parameters, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) qPCR, and infectivity analysis were performed in the acute phase of the disease and in series. Results: Semen parameter values did not differ significantly between subjects with mild COVID-19 and the control group. The serial examination of semen parameters revealed no significant changes between 4, 18, and 82 days after the onset of symptoms. SARS-CoV-2 RNA or infectious particles could not be detected in any ejaculate. Conclusion: Mild COVID-19 seems to have no detrimental effect on semen parameter values.
- Subjects
SARS-CoV-2; SEMEN analysis; COVID-19; VIROIDS; MALE infertility
- Publication
Basic & Clinical Andrology, 2023, Vol 33, Issue 1, p1
- ISSN
2051-4190
- Publication type
Article
- DOI
10.1186/s12610-023-00190-2