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- Title
Combined medico-surgical strategy for invasive sino-orbito-cerebral breakthrough fungal infection with Hormographiella aspergillata in an acute leukaemia patient.
- Authors
Heiblig, M.; Bozzoli, V.; Saison, J.; Thomas, X.; De Croze, D.; Traverse‐Glehen, A.; Cosmidis, A.; Chidiac, C.; Ferry, T.; Alanio, A.; Bienvenu, A. L.; Dupont, D.; Ducastelle‐Lepretre, S.; Michallet, M.; Ader, F.
- Abstract
Hormographiella aspergillata is a rare causative agent of invasive filamentous breakthrough infection, mostly arising after echinocandin exposure. We report a neutropenic patient who developed a severe sino-orbito-cerebral H. aspergillata infection while receiving empirical caspofungin, successfully controlled by an aggressive strategy associating surgical debridement and combined high-dose regimen of antifungal drugs.
- Subjects
ASPERGILLOSIS; ACUTE myeloid leukemia; GRAFT versus host disease; HEMATOPOIETIC stem cell transplantation; ECHINOCANDINS; PATIENTS; BREAKTHROUGH infections
- Publication
Mycoses, 2015, Vol 58, Issue 5, p308
- ISSN
0933-7407
- Publication type
Article
- DOI
10.1111/myc.12305