We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The rate of adaptive evolution in animal mitochondria.
- Authors
James, Jennifer E.; Piganeau, Gwenael; Eyre‐Walker, Adam
- Abstract
We have investigated whether there is adaptive evolution in mitochondrial DNA, using an extensive data set containing over 500 animal species from a wide range of taxonomic groups. We apply a variety of McDonald-Kreitman style methods to the data. We find that the evolution of mitochondrial DNA is dominated by slightly deleterious mutations, a finding which is supported by a number of previous studies. However, when we control for the presence of deleterious mutations using a new method, we find that mitochondria undergo a significant amount of adaptive evolution, with an estimated 26% (95% confidence intervals: 5.7-45%) of nonsynonymous substitutions fixed by adaptive evolution. We further find some weak evidence that the rate of adaptive evolution is correlated to synonymous diversity. We interpret this as evidence that at least some adaptive evolution is limited by the supply of mutations.
- Subjects
ANIMAL adaptation; BIOLOGICAL evolution; MITOCHONDRIAL DNA; ANIMAL species; ANIMAL classification; ANIMAL mutation
- Publication
Molecular Ecology, 2016, Vol 25, Issue 1, p67
- ISSN
0962-1083
- Publication type
Article
- DOI
10.1111/mec.13475