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- Title
Adipose stem cells for bone tissue repair.
- Authors
Ciuffi, Simone; Zonefrati, Roberto; Brandi, Maria Luisa
- Abstract
Adipose-derived stem/stromal cells (ASCs), together with adipocytes, vascular endothelial cells, and vascular smooth muscle cells, are contained in fat tissue. ASCs, like the human bone marrow stromal/stem cells (BMSCs), can differentiate into several lineages (adipose cells, fibroblast, chondrocytes, osteoblasts, neuronal cells, endothelial cells, myocytes, and cardiomyocytes). They have also been shown to be immunoprivileged, and genetically stable in long-term cultures. Nevertheless, unlike the BMSCs, ASCs can be easily harvested in large amounts with minimal invasive procedures. The combination of these properties suggests that these cells may be a useful tool in tissue engineering and regenerative medicine.
- Subjects
ADIPOSE tissue diseases; BONE marrow -- Preservation; BONE marrow transplantation; MESENCHYMAL stem cells; TISSUE engineering; FIBROBLASTS; GENETICS
- Publication
Clinical Cases in Mineral & Bone Metabolism, 2017, Vol 14, Issue 2, p217
- ISSN
1724-8914
- Publication type
Article
- DOI
10.11138/ccmbm/2017.14.1.217