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- Title
Increased Expression of Integrin α6β64 in the Basement Membrane Zone Lining the Sebaceous Glands in Hidradenitis Suppurativa.
- Authors
Blok, Janine L.; Janse, Ineke C.; Horváth, Barbara; Jonkman, Marcel F.
- Abstract
The article discusses a study on the expression of the most important Basement Membrane Zone (BMZ) components including type 17 collagen, type 7 collagen, laminin-332 and integrin a6b4 of the follicular epidermis in Hidradenits Superativa. It indicates the upregulation of integrin a6B4 in sebaceous glands of patients with HS which may result from alterations in the skin microbioma and contribute to the inflammatory reaction seen in HS.
- Subjects
INTEGRINS; COLLAGEN; HIDRADENITIS suppurativa; BACTERIAL diseases; SEBACEOUS glands
- Publication
Acta Dermato-Venereologica, 2015, Vol 95, Issue 8, p994
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-2186