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- Title
A review on curcumin – Antidepressant bioenhancer activity.
- Authors
Anusha, S.; Dhanalakshmi, S.; Harikrishnan, N.; Logesh, V.; Ganesh, S.; Shakthi Priya, P.; Janani, N.; Srinivasan, M.; Prabakaran, S.
- Abstract
A depressive disorder is a prevalent psychiatric disorder, which affects 21% of the world population. The presently using drugs can impose a variety of side-effects, including cardiac toxicity, hypopiesia, sexual dysfunction, body weight gain, and sleep disorder. During the past decade, there is a growing interest in the therapeutic effects of natural products on mental disorders. Curcumin, the principal curcuminoid found in spice turmeric, has recently been studied for its active role in the treatment of various central nervous system disorders. Curcumin demonstrates neuroprotective action in Alzheimer’s disease, tardive dyskinesia, major depression, epilepsy, and other related neurodegenerative and neuropsychiatric disorders. The present review attempts to discuss some of the potential protective role of curcumin in animal models of major depression, tardive dyskinesia, and diabetic neuropathy. These studies call for well planned for pharmaceutical, pharmacological, and clinical studies on curcumin for its potential use in neurological disorders.
- Subjects
ALZHEIMER'S disease; TARDIVE dyskinesia; SLEEP disorders; CURCUMIN; NATURAL products; NEUROLOGICAL disorders; TURMERIC
- Publication
Drug Invention Today, 2020, Vol 13, Issue 4, p571
- ISSN
0975-7619
- Publication type
Article