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- Title
Free radical scavenging activity of developed herbal formulation.
- Authors
Subramani, Sasikala; Nachimuthu, Kannikaparameswari
- Abstract
Objective: Medicinal plants have played a key role in the prevention and treatment of diseases since ancient period. They are also potential sources of drugs and nutrients. Boerhavia diffusa and Achyranthes aspera are widely used medicinal plants in Ayurvedic treatment for a variety of ailments including kidney diseases. The present study was designed to assess the free radical scavenging capacity of herbal formulated medicinal plants, B. diffusa and A. aspera. Materials and Methods: Ethanolic extracts of herbal formulation were prepared and evaluated for their free radical scavenging capacity using various in vitro chemical assays such as 2,2-diphenyl-1-picrylhydrazyl, 2,2'-azinobis(3-ethylbenzothiazolin-6-sulfonic acid), ferric reducing antioxidant power, hydroxyl radical, and superoxide anion radical scavenging activities. Results: The ethanolic extract of herbal formulation showed potential radical scavenging activity against the radicals generated in vitro as the result was compared with the standard at the same concentration. Conclusion: The present research concluded that herbal formulated medicinal plants, B. diffusa and A. aspera, were found to be more effective due to the combined activity of the individual components. Hence, it is concluded that herbal formulation of these plants may provide efficient, supportive, or alternative treatment procedures for numerous health ailments.
- Subjects
HYDROXYL group; RADICAL anions; MEDICINAL plants; THERAPEUTICS; KIDNEY diseases; FREE radicals; SUPERCRITICAL fluid extraction
- Publication
Drug Invention Today, 2020, Vol 14, Issue 2, p232
- ISSN
0975-7619
- Publication type
Article