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- Title
Clinical Results and MRI Evolution of a Nano-Composite Multilayered Biomaterial for Osteochondral Regeneration at 5 Years.
- Authors
Kon, Elizaveta; Filardo, Giuseppe; Di Martino, Alessandro; Busacca, Maurizio; Moio, Antonio; Perdisa, Francesco; Marcacci, Maurilio
- Abstract
The article evaluates the stability of the initial clinical improvement over time through documenting the imaging evolution of tissue regeneration process using magnetic resonance imaging analysis for up to 5 years. It examines 27 patients treated for knee chondral or osteochondral lesions. It looks at the use of osteochondral scaffold to treat chondral and osteochondral knee defects. Statistical improvement in all clinical scores during the two- and five-year follow-ups is also discussed.
- Subjects
ITALY; COLLAGEN; CALCIUM compounds; ANALYSIS of variance; BONE regeneration; EXPERIMENTAL design; FISHER exact test; MAGNETIC resonance imaging; HEALTH outcome assessment; RESEARCH funding; STATISTICS; U-statistics; ARTICULAR cartilage injuries; DATA analysis; STATISTICAL significance; TREATMENT effectiveness; REPEATED measures design; DATA analysis software; FUNCTIONAL assessment; DESCRIPTIVE statistics; THERAPEUTICS
- Publication
American Journal of Sports Medicine, 2014, Vol 42, Issue 1, p158
- ISSN
0363-5465
- Publication type
Article
- DOI
10.1177/0363546513505434