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- Title
CYTOMORPHOMETRY OF BUCCAL SMEARS OF NICOTIANA TABACUM (NASWAR) USERS: A PILOT STUDY.
- Authors
MASOOD, RABIA; ZAIB, NADIA; JAFFAR, ROZINA; KHAN, KHOLA AHMED; JAVED, MUNNAZZA; RAZA, ALI; UMER, NAILA
- Abstract
The objective of the current study was to asses the cytomporphometric changes in buccal mucosal smears of naswar users. The study groups consisted of 24 subjects divided into two groups i.e A control group and B naswar users of ages between 15yrs-60yrs. Cellular diameter CD,nuclear diameter ND and nuclear to cytoplasmic ratio N/C ratio was assessed in buccal mucosal smears taken from clinically normal mucosa of naswar users and normal subjects using exfoliative cytology. The mean cellular diameter of group A and B was 43.93µm and 44.13µm respectively. The mean nuclear diameter of control group and naswar users was 9.99µm and 11.88µm respectively.And the mean N/C ratio of group A and B was 1: 4.42 and 1: 3.71 respectively. The independent T test showed significant results (p ≤ 0.000) for nuclear diameter ND and N/C ratio both. Cytomorphometric changes in cellular diameter, nuclear diameter and N/C ratio assessed by our study depict only cause effect relationship between naswar and and association of these changes with dysplasia or premamlignancy needs further verification with the help of specific immunomarkers.
- Subjects
BUCCAL administration; CYTOPLASM; CYTOLOGICAL research; DYSPLASIA; NASAL mucosa
- Publication
Pakistan Oral & Dental Journal, 2014, Vol 34, Issue 3, p445
- ISSN
1012-8700
- Publication type
Article